https://pmc.ncbi.nlm.nih.gov/articles/PMC10931630/
Special Issue “Molecular Biology in Forensic Science" March 1st, 2024
Molecular Biology has been a revolutionary tool in contributing to advancing forensic science. It has been used for criminal investigations, paternity complications, identifying missing people, and justifying those that are wrongly convicted. Earlier techniques that were used were restriction fragment length polymorphisms, while today electrophoresis and next-generation sequencing has become the standard to forensics. Through better identification of species, miRNA has been used as a stable biomarker for forensic investigations and clinical diagnoses. These biological approaches have promising potential in strengthening the reliability of science in both the legal and healthcare field.
Importance: This article shows the importance of how impactful molecular biology concepts can be in forensics. They improve the approach to investigating and diagnosing, make conclusions in crime scenes more reliable, and can be used outside the forensic science field like for population genetics and speciation. I believe that molecular biology can enforce justice in the legal system. It is very common for people to get wrongly convicted with crimes due to limited evidence. However, molecular biology can provide detailed breakdowns of DNA and allow a safe society because it shows who actually committed the crimes.
I learned more information about how the emerging technologies in NGS and microRNA work to provide DNA and identification analysis. Questions I have are: Why are miRNA better as biomarkers? Can other fields like chemistry be applied to forensics?
Vocab:
forensic: Latin word of "forensis" relating to law
pathology: "patho" is a disease. The study of diseases
Biomarker: "bio" life, "marker" indicator. Measures things in organisms
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